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产品目录

重组大鼠SDF-1β/CXCL12β图片
产品货号:
GS4528
中文名称:
重组大鼠SDF-1β/CXCL12β
英文名称:
Recombinant Rat Stromal-Cell Derived Factor-1 beta/CXCL12β
产品规格:
2μg
发货周期:
1~3天
产品价格:
询价
分子量:Approximately 8.4kDa,a single non-glycosylated polypeptide chain containing 72 amino acids.
储存条件:冷冻(-20℃)

概述

CXCL12 also known as SDF-1 is belonging to the CXC chemokine family.Rat CXCL12 is expressed as two isoforms that differ only in the C-terminal tail.And both SDF-1 isoforms undergo proteolytic processing of the first two N-terminal amino acids.In all SDF-1 isoforms,SDF-1β is the canonical sequence.It has the complete amino acids in the C-terminal tail.On the cell surface,the receptor for this chemokine is CXCR4 and syndecan4.CXCL12 is strongly chemotactic for T-lymphocytes,monocytes,but not neutrophils.SDF-1 is highly conserved between species,murine CXCL12β shares approximately 96%amino acid sequence identity with human CXCL12β.

使用说明

This material is offered by Biorab Biotech for research,laboratory or further evaluation purposes.NOT FOR HUMAN USE.

技术规格

外观Sterile Filtered White lyophilized(freeze-dried)powder.
纯度>97%by SDS-PAGE and HPLC analyses.
来源Escherichia coli.
生物活性Fully biologically active when compared to standard.The biological activity determined by a chemotaxis bioassay using human peripheral blood monocytes is in a concentration range of 100-200ng/ml.
成分Lyophilized from a 0.2μmfiltered concentrated solution in 20mMPB,pH 7.4,150 mM NaCl.
内毒素Less than 1 EU/μg of rRtSDF-1β/CXCL12β as determined by LAL method.
复溶We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom.Reconstitute in sterile distilled water or aqueous buffer containing 0.1%BSA to a concentration of 0.1-1.0mg/mL.Stock solutions should be apportioned into working aliquots and stored at ≤ -20?C.Further dilutions should be made in appropriate buffered solutions.
氨基酸序列KPVSLSYRCP CRFFESHVAR ANVKHLKILN TPNCALQIVA RLKSNNRQVC IDPKLKWIQE YLDKALNKRL KM
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